---
title: "Medical Weight Loss, GLP-1 Dosing Guide"
date: 2026-05-27T10:51:00+01:00
author: Paulina Charlesworth
canonical_url: "https://drcharlesworth.co.uk/weight-loss/glp1-dosing-guide"
section: Weight Loss
---
GP-Led Programme

## Safe, Personalised Guidance for Mounjaro, Wegovy & Ozempic

GLP-1 and dual-agonist weight loss medications, Mounjaro (Tirzepatide), Wegovy (Semaglutide) and Ozempic (Semaglutide) are some of the most effective medical treatments available for weight loss. But the results you achieve, and how comfortably you achieve them, depend heavily on choosing the right dose at the right time.

At her GP-led clinic in Sevenoaks, Dr Paulina Charlesworth prescribes and monitors GLP-1 medications with a personalised dosing plan built around your health, goals and tolerance. This avoids unnecessary side effects and ensures treatment remains both safe and effective.

**Why GLP-1 Dosing Needs Medical Supervision**

Correct dosing influences:

- How well you tolerate the medication
- Whether you avoid preventable side effects
- The speed and sustainability of weight loss
- How effectively hunger, cravings and glucose regulation improve

Side effects such as nausea, reflux, constipation, fatigue and low appetite usually occur when:

- doses are increased too quickly
- the initial dose is too high
- pre-existing health conditions were not considered
- there is no medical review before escalating

A tailored dosing plan reduces these risks significantly.

##### Medicines and Healthcare products Regulatory Agency (MHRA)

All GLP-1 medicines are prescription only medicines, which means they can only be prescribed by a healthcare professional.

 

Personalised titration plan

## How Dosing Works at Dr Paulina’s Clinic

Every patient receives a personalised titration plan, which may differ from standard pharmacy-issued schedules.

Your plan is based on:

- your BMI, metabolic profile and medical history
- how strongly you respond to the medication
- your appetite and blood sugar patterns
- your side-effect profile
- your rate of weight loss
- your longer-term goals (fat loss, maintenance, metabolic health)

Dosing is adjusted only when clinically appropriate, and never rushed.

**Why Work With a GP Instead of Pharmacy-Only Services**

Many online providers offer “standardised” dosing schedules without medical context. Dr Paulina provides something very different:

**A full medical assessment before prescribing**

Medications are prescribed only when safe and appropriate

**Custom dosing, not automated escalation**

You are not pushed to the next dose if your body isn’t ready.

**Early intervention for side effects**

Symptoms are addressed quickly with medical strategies, medication adjustments or anti-nausea support.

**Review of other health factors**

Including hormones, thyroid, nutrient deficiencies, perimenopause, ADHD-related eating patterns, and more.

**Continuous support**

You have a doctor to contact not a chatbot or a pharmacy queue.

**Better long-term results**

Studies show personalised dosing improves success and reduces dropout.

This is the key difference between GP-led care and buy-online pharmacy models.

**Typical GLP-1 Dose Progression**

**Starting dose:**  
A low dose of Mounjaro, Wegovy or Ozempic to allow the body to adjust gradually.

**Titration phase:**  
Dose increases only when:

- side effects are controlled
- the previous dose is no longer suppressing appetite effectively
- you are medically stable
- weight loss has plateaued and it is appropriate to escalate

**Maintenance phase:**  
Not every patient needs the highest licensed dose.

Some achieve excellent results and long-term stability at mid-range dosing.

**Tapering or transition:**  
Once goals are reached, some patients transition to:

- a lower maintenance dose
- alternative medications (if appropriate)

Dr Paulina works with you to minimise regain and ensure sustainability.

**Which Medication Is Right for Me?**

Each GLP-1 works slightly differently:

**Mounjaro (Tirzepatide)**

Dual GIP/GLP-1 agonist, often the strongest appetite and cravings reduction.

**Wegovy (Semaglutide)**

Weekly GLP-1, effective for appetite control and emotional eating.

**Ozempic (Semaglutide)**

GLP-1 similar to Wegovy, commonly used off-label for weight loss under medical care.

Your medical history and goals determine which option is recommended.

GLP-1 Dosing

## Frequently Asked Questions

- How quickly should I increase my dose? There is no fixed rule, it depends on your response. Some patients increase every 4 weeks; others stay longer at lower doses. Escalation is only done when medically appropriate.
- Can I stay on a lower dose long-term? Yes. Many patients do extremely well on mid-range maintenance dosing.
- What if I experience nausea or reflux? Side effects are common if doses rise too quickly. Dr Paulina can adjust your schedule or prescribe supportive treatments.
- Do I need a BMI of 35 like the NHS requires? No. Private prescribing follows different criteria. Dr Paulina assesses suitability individually.
- Can I switch between Wegovy, Ozempic or Mounjaro? Yes, switching may be appropriate depending on tolerance and results.